A surgery to remove an injured or affected liver and replace it with a whole new or just a segment of a liver from a donor is known as liver transplantation. People who are suffering from either acute or chronic liver failure may need the liver transplant.
Acute liver failure (ALF) occurs suddenly and is said to be caused by the intake of drugs or by thehepatitis virus. Chronic liver failure (CLF), also called last/end-stage liver disease, advances over months, years or decades. It has various causes which include—viral causes like hepatitis B and hepatitis C, toxic and drugs, and improper metabolic conditions.
While in children, biliary atresia is the most occurring cause of liver failure which further leads to liver transplantation. In this, bile ducts are absent, blocked or damaged in new-borns, which as a result let the toxic bile builds up in the liver resulting in cirrhosis. Other reasons for liver transplantation include cancers that originate in the liver like—hepatocellular carcinoma, hepatoblastoma and cholangiocarcinoma.
The signs and symptoms of thefailure of theliver may include—jaundice, fatigue, weakness, loss of appetite, nausea, weight loss, muscle loss, itching, etc. Those who happen to get a liver transplantation first are carefully evaluated by doctors who typically include assessment of the status of person’s disease; the probability of person’s survival after transplantation; person’s emotional and mental health; and the support system of the person.
However, one might get a transplantation or not, this depends totally on the person and the disease he’s suffering with. One might not be considered for liver transplantation if he has cancer outside the liver, infection outside the body, any advanced lung or heart disease, AIDS or a lack of support psychosocially. Later, the transplant candidate may decide to go forward or to avoid transplantation.